Research Program Reports
The FSCJ has developed a road map, “Strategic direction for promoting research and survey to ensure food safety”. (PDF：250KB)
Seven to eight programs are selected annually. Research period is approximately two years.
The research grant program is implemented to collect scientific evidence necessary for conducting risk assessment and developing assessment guidelines.
Research programs completed in FY 2020
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2019–2020
|
1902
|
Elucidation of Safety Assessment Points for the Foods Obtained from the Transgene‐free, Phenotype‐transformed Plants
|
|
|
FY 2019–2020 |
1905 |
Mechanism Underlying the Demethylation of Methylmercury and Evaluation of Biogenic Mercury Selenide Toxicity in Foods |
|
|
FY 2019-2020
|
1907 |
Research on Development of Software Calculating
the Benchmark Dose Using Dichotomous Response Data
|
|
Research programs completed in FY 2019
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2017–2019
|
1706
|
Study on migration test in risk assessment for synthetic resin for apparatus, containers and packaging
|
|
|
FY 2018–2019 |
1801 |
Study on the development of new evaluation support technol-ogy: Examination of database utilization method for toxicity prediction |
(Partly in Japanese)
|
|
FY 2018-2019
|
1802
|
Development of a new dose-response model based on survival characteristics of Campylobacter during food digestion process
|
(Partly in Japanese)
|
|
FY 2018–2019
|
1803 |
Study on application of in silico evaluation method to risk assessment of trace level chemicals unintentionally contained in food.
|
|
|
FY 2018–2019
|
1804
|
Research on application condition of the benchmark dose methods for health risk assessment |
|
|
FY 2018–2019
|
1806
|
Research for quantitative risk analysis of Campylobacter food poisoning in Japan
|
|
| FY 2018–2019 | 1807 | Studies on fruit allergen components associated with a risk of severe allergies |
Abstract (PDF：457KB)
|
| FY 2018–2019 | 1808 |
Study on the risk assessment for modified fumonisins
|
Abstract (PDF：161KB)
|
| FY 2019 | 1901 |
Study on risk assessment for food additives focusing on transferring to the body. |
Abstract (PDF：151KB)
|
Research programs completed in FY 2018
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2016–2018
|
1607
|
Historical control data from rat reproductive and developmental toxicity testing, and research into toxicologically significant skeletal variations, such as thoracolumbar supernumerary ribs
|
|
|
FY 2017–2018 |
1702 |
In vitro approach to estimate the human transmission risk of prions |
|
|
FY 2017–2018
|
1703
|
The study of emergence trends and characterization of col-istin-resistantbacteria |
|
|
FY 2017–2018
|
1704 |
Assessment of inorganic arsenic exposure in Japan and development of its methodology |
|
|
FY 2017–2018
|
1705
|
Studies on difference in the mechanisms between food allergy and oral tolerance and the mechanisms of anaphylactic reac-tions induced by food allergens |
|
| FY 2018 | 1805 | Study on methods for safety assessments of food additives – Proposal for methods for safety assessments in infant formula and guidelines of toxicological studies based on international trends. |
Abstract (PDF：112KB)
|
Research programs completed in FY 2017
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2015–2017
|
1503
|
Cancer risk assessment of dietary acrylamide intake based on large-scale prospective cohort study, development of dietary acrylamide exposure assessment method, and evaluation of their validity |
|
|
FY 2016–2017 |
1601 |
Bioavailability and hazard assessment of nine naturally occurring selenium compounds |
|
|
FY 2016–2017
|
1602
|
Construction of the database of in vivo toxicity tests and its application to the in silico prediction and evaluation of in vivo toxicity |
|
|
FY 2016–2017
|
1603 |
Study on estimation of intake of chemical substances migrated from PET bottles |
|
|
FY 2016–2017
|
1604
|
Elucidation of carcinogenic mechanisms of organic arsenicals |
|
|
FY 2016–2017
|
1605
|
Establishment and evaluation of a novel toxicity evaluation system for chemical substances based on the expression changes of plasma microRNAs |
|
| FY 2016–2017 | 1606 |
Bacitracin-resistant enterococci in livestock (meats samples) and the multiple-drug resistant pheromone-responsive highly conjugative plasmids in Japan |
Abstract (PDF：42KB)
|
| FY 2017 | 1701 | Research for establishing the methods of risk assessment for food allergens |
Abstract (PDF：55KB)
|
Research programs completed in FY 2016
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2013–2016
|
1301
|
Quantitative assessment of Atypical Bovine spongiform encephalopathy infectivity to human with humanized genetically-modified mice
|
|
|
FY 2015–2016 |
1501 |
Development of the new tiered approach for toxicity studies of pesticide considering species difference in "toxicity profile" and "toxicity dose-response" - evaluation of necessity of 1-year toxicity study in dogs and carcinogenicity study in mice. - |
|
|
FY 2015–2016
|
1504
|
Space-time genomic comparative analyses about circulation of antimicrobial resistant bacteria between livestock and human |
|
|
FY 2015–2016
|
1505 |
Mechanisms and pathogenesis of food allergy in infants, and risk factors of its crisis |
|
|
FY 2015–2016
|
1506
|
Establishment of a new assay system for IgE-allergenicity in foods |
|
|
FY 2015–2016
|
1507
|
Estimation of dietary exposure to acrylamide in the Japanese population |
|
Research programs completed in FY 2015
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2014–2015
|
1402
|
Studies of a new screening method for compounds with teratogenicity through changing retinoic acid concentration and the molecular mechanism
|
|
|
FY 2014–2015
|
1403
|
Studies for risk assessment of ciguatera fish poisoning
|
|
|
FY 2014–2015
|
1404
|
Newly emerging allergy/allergy-like reactions provoked by food intake.
|
|
|
FY 2014–2015
|
1406
|
Modelling the survival kinetics and probability of Salmonella enterica and enterohemorrhagic Escherichia coli under desiccation environment and on low water activity foods
|
|
|
FY 2014–2015
|
1407
|
Cancer Risk assessment of food-derived dimethylmonothioarsinic acid
|
|
|
FY 2015
|
1502
|
Draft guidelines on safety assessments of nutrients and processing aids
|
|
| FY 2015 | 1508 | Study on the intake estimation method for the evaluation of flavouring |
Abstract (PDF：40KB)
|
Research programs completed in FY 2014
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2013–2014
|
1302
|
Toxicological characterization of chemical-induced liver hypertrophy: studies based on the analyses of nuclear receptor activation and enzyme induction
|
|
|
FY 2013–2014
|
1303
|
Establishment of interpretation on chemical induced hepatocellular hypertrophy and its future issues to be solved in risk assessment in Japan
|
|
|
FY 2013–2014
|
1304
|
A study on the risk assessment method of genotoxic carcinogens
|
|
|
FY 2013–2014
|
1305
|
Establishment of the quantitative risk assessment model of antimicrobial-resistant bacteria derived from food-producing animals
|
|
|
FY 2014
|
1401
|
Study on the procedure for the risk assessment of flavorings in Japan
|
|
|
FY 2014
|
1405
|
Establishment and refinement of novel evaluation system of hepatotoxicity, based on functional properties of hepatic macrophages
|
|
| FY 2014 | 1408 | Estimation of the daily intake of acrylamide in Japan |
Abstract (PDF：67KB)
|
Research programs completed in FY 2013
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2011-2013
|
1101
|
Study about the virulence of the particular serovars of Listeria monocytogenes isolates, and the consideration about the vaccination effect of the host.
|
|
|
FY 2011-2013
|
1102
|
Risk assessment of the ingestion of foods containing arsenosugers and arsenolipids
|
|
|
FY 2011-2013
|
1103
|
Development of a risk assessment model based on the extrapolation of the metabolic profile of humanized-liver chimeric mice
|
|
|
FY 2011-2013
|
1104
|
Development of combined genotoxicity and repeated dose toxicity study in rats
|
|
|
FY 2012-2013
|
1201
|
Dose-response analysis in low doses of oxidative stress-inducing genotoxic substance
|
|
|
FY 2012-2013
|
1202
|
Survey of contamination by parasites in livestock and game meat and development of risk assessment method for meat-borne parasitic diseases based on the epizootic and epidemiological characteristics
|
|
|
FY 2012-2013
|
1203
|
Development and application of genetic methods to detect infectious viruses for risk analysis of foodborne viruses in foods
|
|
|
FY 2012-2013
|
1204
|
Usage of safety factor for evaluation of non-observed adverse effect level (NOAEL) in risk assessment of chemicals to high risk group people of life style related diseases.
|
Research programs completed in FY 2012
|
Research period
|
Research project No.
|
Title of research project
|
Research report
|
|
FY 2010-2012
|
1001
|
Development of novel method monitoring the effect of exposure of agricultural chemicals on developmental brain using gene-expression monitoring mice
|
|
|
FY 2010-2012
|
1002
|
Study on offspring reproductive and developmental effects of fetal and lactational exposure to di(2-ethylhexyl)phthalate and the rrisk assessment
|
|
|
FY 2010-2012
|
1003
|
Development of the assay system to evaluate the effects of perinatal exposure to chemical compounds on the social and emotional activities
|
|
|
FY 2010-2012
|
1005
|
Development of method for toxicokinetic evaluation of nanomaterials and sub-nanomaterials following oral administration for safety evaluation
|
|
|
FY 2010-2012
|
1006
|
Safety assessment studies of glycidol fatty acid esters and 3-MCPD fatty acid esters
|
|
|
FY 2010-2012
|
1007
|
Research on application of the benchmark dose approach in the dose response assessment
|
|
|
FY 2010-2012
|
1008
|
Development for the evaluation method of immunomodulatory effects of nanomaterials by oral ingestion
|
|
|
FY 2010-2012
|
1009
|
The effects of TFAs on cardiovascular disease in Japan NOW.
|
|
|
FY 2011-2012
|
1105
|
Preparation of Guidance for ARfD Setting for Pesticides, Etc.,in Japan
|
|
|
FY 2011-2012
|
1106
|
Evaluation of aluminum toxicity to neuronal development and estimation of aluminum exposure in population in Japan
|
|
|
FY 2011-2012
|
1107
|
Development of placental permeability evaluation techniques for analyzing species differences
|
|
Disclaimer
These reports summarize an outcome of a research or a survey program funded by the FSCJ. Conclusions and opinions in these reports are those of the individual researchers only and do not reflect the policies or view of the FSCJ. All rights are reserved by the FSCJ. |
