食品安全関係情報詳細
| 資料管理ID | syu06760103535 |
| タイトル | 英国毒性委員会(COT)、ビスフェノールA(BPA)に関するCOTポジションペーパーへの補足声明書を公表【1/3】 (4/4) |
| 資料日付 | 2026年7月6日 |
| 分類１ | - |
| 分類２ | - |
| 概要（記事） | (この記事は 4 / 4 ページ目です) (前ページの内容:https://www.fsc.go.jp/fsciis/foodSafetyMaterial/show/syu06760102535) (文献7) L. Gao et al., (2020), The imbalance of Treg/Th17 cells induced by perinatal bisphenol A exposure is associated with activation of the PI3K/Akt/mTOR signaling pathway in male offspring mice. Food and Chemical Toxicology, 137, 111177. https://doi.org/10.1016/j.fct.2020.111177 (文献8) Y. Malaise et al., (2017a), Gut dysbiosis and impairment of immune system homeostasis in perinatally-exposed mice to Bisphenol A precede obese phenotype development. Scientific Reports, 7 (1), 14472. https://doi.org/10.1038/s41598-017-15196-w (文献9) S. Luo et al., (2016), Gestational and lactational exposure to low-dose bisphenol A increases Th17 cells in mice offspring. Environmental Toxicology and Pharmacology, 47, 149-158. https://doi.org/10.1016/j.etap.2016.09.017 (文献10) Y. Dong et al., (2023), Increased levels of IL-17 and autoantibodies following Bisphenol A exposure were associated with activation of PI3K/AKT/mTOR pathway and abnormal autophagy in MRL/lpr mice. Ecotoxicology and Environmental Safety, 255, 114788. https://doi.org/10.1016/j.ecoenv.2023.114788 (文献11) G. Wang et al., (2020), Maternal vitamin D supplementation inhibits bisphenol A-induced proliferation of Th17 cells in adult offspring. Food and Chemical Toxicology, 144, 111604. https://doi.org/10.1016/j.fct.2020.111604 (文献12) J. Bodin et al., (2014), Transmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice. Toxicological Science, 137(2), 311-323. https://doi.org/10.1093/toxsci/kft242 (文献13) E. O’Brian et al., (2014), Perinatal bisphenol A exposure beginning before gestation enhances allergen sensitisation, but not pulmonary inflammation, in adult mice. Journal of Developmental Origins of Health and Disease, 5(2), 121-131. https://doi.org/10.1017/s204017441400004x (文献14) Y. Malaise et al., (2017b). Consequences of bisphenol a perinatal exposure on immune responses and gut barrier function in mice. Archives of Toxicology, 92(1), 347-358. https://doi.org/10.1007/s00204-017-2038-2 (文献15) X. Ye et al., (2023), Nutrient-sensing ghrelin receptor in macrophages modulates bisphenol A-induced intestinal inflammation in mice. Genes, 14, 1455. https://doi.org/10.3390/genes14071455 (文献16) H. J. Gu et al., (2024), Genome-wide transcriptome analysis reveals that Bisphenol A activates immune responses in skeletal muscle. Environmental Research, 252(3), 119034. https://doi.org/10.1016/j.envres.2024.119034 |
| 地域 | 欧州 |
| 国・地方 | 英国 |
| 情報源（公的機関） | 英国毒性委員会（COT） |
| 情報源（報道） | 英国毒性委員会（COT） |
| URL | https://www.gov.uk/government/publications/supplementary-statement-to-the-cots-position-paper-on-bisphenol-a-bpa/supplementary-statement-to-the-cots-position-paper-on-bisphenol-a-bpa |