食品安全関係情報詳細
| 資料管理ID | syu06590031535 |
| タイトル | 英国毒性委員会(COT)、「英国における飲料水基準の策定を支援するためのホウ素に関する健康影響に基づく指標値の導出」と題するディスカッションペーパーを公表 (後半2/2) |
| 資料日付 | 2025年9月4日 |
| 分類１ | - |
| 分類２ | - |
| 概要（記事） | (前半の内容:https://www.fsc.go.jp/fsciis/foodSafetyMaterial/show/syu06590030535) (※補足1) COT, (1995), Annual report: Boron in drinking water and food. p. 6. https://cot.food.gov.uk/sites/default/files/cot/cotannualreport1995.pdf (※補足2) J. J. Heindel et al., (1992), Developmental toxicity of boric acid in mice and rats, Fundamental and Applied Toxicology, 18(2), 266-277. https://www.sciencedirect.com/science/article/abs/pii/027205909290055M (※補足3) C. J. Price et al., (1996), Developmental toxicity NOAEL and postnatal recovery in rats fed boric acid during gestation, Fundamental and Applied Toxicology, 32(2), 179-193. https://www.sciencedirect.com/science/article/abs/pii/S0272059096901219 (※補足4) R. J. Weir, Jr. and R. S. Fisher, (1972), Toxicologic studies on borax and boric acid, Toxicology and Applied Pharmacology, 23(3), 351-364. https://www.sciencedirect.com/science/article/abs/pii/0041008X72900373 (※補足5) World Health Organization (WHO), (1993), Guidelines for drinking-water quality, 2nd edition, Volume 1, pp. 43-44. https://iris.who.int/server/api/core/bitstreams/d0497a1b-f275-486c-9bfa-beba4fddd5f8/content (※補足6) European Center for Ecotoxicology and Toxicology of Chemicals (ECETOC), (1995), Reproductive and general toxicology of some inorganic borates and risk assessment for human beings (Technical Report No. 63). https://www.ecetoc.org/publication/tr-063-reproductive-and-general-toxicology-of-some-inorganic-borates-and-risk-assessment-for-human-beings/ (※補足7) Expert Group on Vitamins and Minerals (EVM), (2003), Safe Upper Levels for Vitamins and Minerals, pp. 164-171. https://cot.food.gov.uk/sites/default/files/vitmin2003.pdf (※補足8) World Health Organization (WHO), (2009), Boron in drinking-water: Background document for development of WHO Guidelines for Drinking-water Quality (No. WHO/HSE/WSH/09.01/2). https://iris.who.int/bitstream/handle/10665/70170/WHO_HSE_WSH_09.01_2_eng.pdf (※補足9) Agency for Toxic Substances and Disease Registry (ATSDR) (2010) Toxicological profile for Boron, U.S. Department of Health and Human Services, Public Health Service. https://www.atsdr.cdc.gov/toxprofiles/tp26.pdf (※補足10) European Food Safety Authority (EFSA) Panel on Food Additives and Nutrient Sources added to Food (ANS), (2013), Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives, EFSA Journal, 11(10), 3407. https://www.efsa.europa.eu/en/efsajournal/pub/3407 (※補足11) Health Canada, (2023), Guidelines for Canadian drinking water quality boron: Overview. https://www.canada.ca/en/health-canada/services/publications/healthy-living/guidelines-canadian-drinking-water-quality-guideline-technical-document-boron.html#a1 (注) 当該資料は、2025年9月9日開催予定の会議(COT Meeting)用の資料であり、COTの意見を反映するものではないことから論文などへの引用は禁止する。 |
| 地域 | 欧州 |
| 国・地方 | 英国 |
| 情報源（公的機関） | 英国毒性委員会（COT） |
| 情報源（報道） | 英国毒性委員会（COT） |
| URL | https://cot.food.gov.uk/Introduction%20and%20Background%20-%20Deriving%20a%20health-based%20guidance%20value%20for%20boron%20to%20support%20development%20of%20UK%20Drinking%20Water%20Standards |